Transgenic animals lecture notes

Lecture 35 transgenic animals introduction transgenic animals are animals most commonly mice that have had a foreign gene deliberately inserted into their genome. What is a transgenic animal br an animal contains a foreign gene genes br introduced purposely by human intervention br ul li transgenic animals are altered so that their dna produce proteins that normally they would not produce li li ul li history of transgenic animal production br 1970 s first transgenic mice via viral infection but not germlinetransmission br 1980 s first transgenic mice via microinjection the most popular technique br 1985 first. Engineering embryos various animals are used in transgenic studies but the most common animal used tends to be mice. Animals that have had their dna manipulated to possess and express a foreign gene are known as transgenic animals. The first transgenic animal was produced in 1983 when genes for human growth hormone were introduced into mice. Transgenic rats rabbits pigs sheep cows and fish have been produced although over 95 percent of all existing transgenic animals are mice. A transgenic animal is an animal in which one or more genes have been introduced into its nonreproductive cells. Example transgenic rats rabbits pigs sheep etc. A transgenic animal is one that carries a foreign gene that has been deliberately inserted into its genome. Transgenic animals are created to study how genes are regulated and how they affect the normal functions of the body and its development. This document is highly rated by biotechnology engineering bt students and has been viewed 1126 times. Moreover in order to devise a cure for these diseases the transgenic animals are used as model organisms. Such animals are most commonly created by the micro injection of dna into the pronuclei of a fertilized egg which is subsequently implanted into the oviduct of a. These transgenic models are used in research for the development of medicines. Transgenic animals lecture notes.

Applications biotechnology engineering bt notes edurev is made by best teachers of biotechnology engineering bt. Transgenic technology has led to the development of fishes live stock and other animals with altered genetic profiles which are useful to mankind. Nov 23 2020 lecture 4 transgenic animals. Foreign genes are inserted into the germ line of the animal so it can be transmitted to the progeny. Transgenic animals lecture notes. For example we have transgenic models for diseases such as alzheimer s and cancer. Transgenic animals can be used to produce valuable products. Sheep goats pigs cows rabbits rats mice fish insects parasites and even humans have previously been used in this modification process. Transgenic animals are specially designed to study the role of genes in the development of certain diseases. Although more than 95 of transgenic animals are mice.

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