Production of transgenic animals notes

Following natural gestation and birth offspring are subject to tissue biopsy and blood sampling. Let us discuss a few of them here. The production of transgenic animals has focused mainly on producing models e g the mouse for basic and medical research. The first transgenic animal was produced in 1983 when genes for human growth hormone were introduced into mice. The transgenic animals are created because of the benefits they provide to the man. Transgenic animals produced with the purpose of producing better and good quality breed increased in milk yield as well as to produce organs to meet the demand for organ transplantation. Theoretically all living beings can be genetically manipulated. There have been numerous reports and applications of transgenic plants in agriculture mainly to benefit the producer. There are several types of transgenic animals like transgenic sheep birds chickens pigs insects etc. Sheep goats pigs cows rabbits rats mice fish insects parasites and even humans have previously been used in this modification process. Animals with manipulated genetic material carrying recombinant dna are known as transgenic animals. A transgenic animal is an animal in which one or more genes have been introduced into its nonreproductive cells. However the realization of genetically engineered livestock has been much slower. The major successes have been achieved in the transfer of. Transgenic animals are just one in a series of developments in the area of biotechnology.

After injecting the dna the embryo is implanted into the uterus of receptive females. Usually ear tissue and blood are screened by polymerase chain reaction and or southern analysis for the presence of the transgene. Es cells are obtained from the inner cell mass of a blastocyst. Then they are inserted into a blastocyst and implanted into a host s uterus to grow normally. The transgenic animals are created because of the benefits they provide to the man. Transgenic animals for the production of therapeutic and diagnostic proteins are produced by transferring fertilized transgene carrying embryos to recipient animals. Transgenic animals can be used to produce valuable products. Transgenic animals can be created by manipulating embryonic stem cells. Production of transgenic animals notes. Transgene is incorporated into the es cell by microinjection by a retro virus by electroporation transgenic stem cells are grown in vitro. Transgenic animals are those that have been genetically modified.

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